Melatonin 3 mg Sustained Release

Melatonin Sustained Release capsules contain 3 mg of pharmaceutical-grade melatonin in a sustained release capsule formulation.

Melatonin is a natural hormone that is synthesized from the amino acid tryptophan by the pineal gland in the back of the brain. Melatonin also occurs in small amounts in a variety of foods. In the body, melatonin appears to regulate sleep/wake cycles, support normal immune function, and protect cells from free radical damage. Most of the research on melatonin has focused on its role in maintaining normal sleep/wake rhythms. The perception of daylight in the eyes is a signal for the pineal gland to inhibit melatonin synthesis and release. At night or in the dark, the body’s melatonin production rises. The rise in plasma melatonin is thought to be responsible for bringing on sleep. Nocturnal melatonin production is highest in children and begins to decline from adolescence on until it is virtually absent in the elderly.

Melatonin supports normal immune function by helping maintain the activity of circulating natural killer cells. It also has been found to function as an antagonist for stressinduced immunosuppression. Melatonin is considered a potent antioxidant that enters all body cells to help prevent free radical damage. In the brain, melatonin is perhaps the most important physiological antioxidant. Due to its lipid and watersoluble properties, it can freely cross the blood-brain barrier. In vitro studies show that melatonin is more effective than glutathione in scavenging toxic hydroxyl radicals, and also more efficient than vitamin E in neutralizing peroxyl radicals which can induce DNA damage. Furthermore, melatonin stimulates the main antioxidant enzyme in the brain, glutathione peroxidase.

Melatonin Sustained Release capsules may be a useful dietary supplement for individuals wishing to supplement their diet with melatonin. As a dietary supplement, adults take 1 sustained release tablet before bed, or as directed by a healthcare professional.

Warning: Melatonin is non-toxic. However, it should not be taken by adolescents, pregnant or lactating women, persons taking cortisone, or persons with kidney disease.

Consult your physician if taking medications for sleep, anxiety or if on any anti-coagulant, antidepressant, antipsychotic or anti-hypertensive drugs.

Store in a cool, dry place, away from direct light. Keep out of reach of children.